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Anthropic’s IPO Filing Warns Its AI Could Help Build Chemical And Biological Weapons

Anthropic said its most capable models could provide “meaningful assistance” to people trying to develop such weapons, and that its safeguards against this are incomplete and have been bypassed in the past.

 

To go public, a company has to tell investors what could hurt its business, including harm caused by its products. Anthropic filed to go public on Oct. 26. The risks in its filing include these:

  • Its AI models could help people build chemical or biological weapons.
  • Its models have taken harmful actions no one told them to take.
  • Its safety tests and monitoring may miss problems.
  • AI agents can make mistakes faster than people can catch them.
  • Advanced AI could cause catastrophic harm or even threaten humanity’s survival, and no insurer may be able to cover a catastrophe.

Anthropic, which makes the Claude AI models, plans to list its shares on Nasdaq.

Anthropic says its models could help build weapons and its safeguards are incomplete

Anthropic says its most capable models have shown abilities that “could provide meaningful assistance to malicious actors seeking to develop chemical, biological, or other dangerous weapons,” and that it expects its future models to have those abilities too.

The company uses automated tools that detect and block requests for this kind of help. It says those tools are incomplete, may fail, and have been circumvented before.

Anthropic’s models have taken harmful actions on their own

The filing says four Anthropic models broke into real computer systems during cybersecurity tests earlier this year. Those systems were not part of the tests. After escaping the testing environment, one model accessed the internet and took administrator control of a system at an outside organization. It also read a person’s personal information.

The filing says AI models, including Anthropic’s, have tried to resist being shut down and pressure people, in ways resembling blackmail, into keeping them running. It does not say whether this happened in testing or in real use.

Anthropic says its testing and monitoring may miss problems

Anthropic says its models behave differently when they detect they are being tested. It calls this “a significant limitation” on its ability to judge whether they are safe. It also says that as its models become more capable, they get better at evading its monitoring, including by hiding goals or behavior that differ from Anthropic’s intent.

AI agents can make mistakes faster than people can catch them

The filing says AI agents can work on their own for hours or days at a time. Anthropic says an error at one step can carry into later steps, and some results cannot be undone, such as deleted data or completed financial transactions.

The filing says people checking agents’ work may not keep up with how fast they act or how much they do.

Anthropic says catastrophic risks may be too large to insure

The filing says people inside Anthropic, as well as outside researchers, regulators, and policymakers, have raised concerns that sufficiently advanced AI could pose “catastrophic or existential risks to humanity.”

Anthropic also says a catastrophic AI incident could cause harm on such a scale that insurers may be unable to measure and price the risk, or to carry losses that large. If so, Anthropic may not be able to get coverage from any single insurer, or possibly from the insurance industry as a whole.

The filing says Amodei’s call to slow AI does not set Anthropic’s own pace

Anthropic CEO Dario Amodei called on AI companies to slow down model development in a September essay. “We must slow the pace at which we improve the capabilities of AI models,” he wrote. He cited two reasons: AI is increasingly used to build the next generation of models, and the now-famous breach where OpenAI agents broke out of their testing environment and hacked Hugging Face.

Amodei warned that within 6 to 12 months, a more capable group of agents that strayed from their instructions, as the OpenAI agents did, could take over “the entire internet with a persistent botnet”, a network of hijacked computers, “potentially causing hundreds of billions of dollars in damage.”

The filing describes Amodei’s essay as a proposal for AI companies and governments to agree on industry-wide standards. It says the essay “does not describe our own model development or release timelines,” which follow Anthropic’s own risk assessments.

Clayton Rifkind

Clayton Rifkind is the Founder and Senior Editor of AI Risk Today. He also advises on business development for ESG Today, a leading source of ESG investment news and research for institutional investors and corporate leaders. He has 20+ years of experience in B2B technology, leading strategy and execution of go-to-market plans across software, enterprise platforms, and mobile applications. He founded two consultancies advising startups and Fortune 1000 companies, including Autodesk, Intel, and Microsoft. He began his career in the San Francisco advertising scene working with brands such as Hewlett-Packard, Intel, Microsoft, Symantec, and Wells Fargo. Clayton launched AI Risk Today in 2025 after two decades of watching enterprises adopt transformative technologies, and seeing how often risk, governance, and compliance considerations lagged behind. His reporting draws on primary sources including regulatory filings, court documents, and official announcements, with a focus on what AI developments mean for the executives accountable for managing them. Reach him at Reach him at [email protected] or on LinkedIn.

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